Which are common manifestations of endometriosis?

• A. Acute infection and fever.
• B. Weight gain.
• C. Frequent migraines.
• D. Dysmenorrhea, heavy irregular periods, chronic fatigue, and infertility.

Answer: (D)

Endometriosis causes tissue similar to the lining of the uterus to grow outside the uterus, leading to cyclical and chronic symptoms tied to menstrual hormones. The most characteristic manifestations are dysmenorrhea (painful periods), heavy or irregular menstrual bleeding, ongoing fatigue from chronic pain (and sometimes anemia), and infertility due to pelvic scarring and adhesions. This combination aligns with the description of dysmenorrhea, heavy irregular periods, chronic fatigue, and infertility, making it the best fit. Acute fever and infection would point to pelvic inflammatory disease rather than endometriosis. Weight changes and frequent migraines aren’t typical defining features of endometriosis.